After 2 rounds of polling here are the current data (with some assumptions about the preferences of Amit, Greg, and Mike)
31/43 consultants (72% response rate)7 (22.5% of respondents) routinely use ketamine and propofol in combination for EDPS
27/31 (87% of respondents) would be willing to be assigned to the K+P arm of the study
30/31 (97% of respondents) would be willing to be assigned to the propofol arm. The one objector just isn’t happy with the dosing schedule, but may be flexible.
25/31 (81% of respondents) would be willing to forgo O2. Those who like their O2 like it very much, and wouldn’t be willing to give it up. There are some who are agreeable to forgoing O2, but are somewhat anxious about it. We’ll probably have to have a broader discussion about supplemental O2 within the group before moving forward (or we could just use O2 and suffer with a diminished power to detect adverse events).
The second round of the poll was pretty well targeted at non-responders. I could send a third round, as it would be nice to get everyone on board.